GPRS
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About gprs package
Get started: understanding the data format
Before step1:
Step1: Unify the data format
Setp 2: Generate Plink bfiles (.bim, .bam, .fam)
Setp 3-1: Clumping (remove linked SNPs)
Setp 3-2: Filter SNPs depends on
.clump
Setp 4-1: Generate PRS model
Setp 4-2: Combined PRS model
Setp 5-1: Calculate statistics value of PRS model
Setp 5-2: Combined PRS statistics results (Optional)
Examples
Example of giant height from Wood
et al
2014
Example of MEC American Africans
API Reference
GPRS
GeneAtlasModel
GwasModel
GPRS
GwasModel
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GwasModel
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